Comments on: What Do We Know About Huperzine A? Potential Uses, Side-Effects, and More

By: Errol Longley

Errol Longley — Tue, 12 Jan 2021 03:01:45 +0000

The treatment of the topic is well done, but may need a refresh as it appears out-of-date. In particular, half life and accumulation are understated. Both areas were accompanied by qualifying disclaimers, true enough.

Here are some Huperzine A references that may be of interest to your readers.

https://www.sciencedirect.com/topics/chemistry/huperzine-a

https://www.huhs.edu/literature/Huperzine%20&%20Vinpocetine.pdf

Again, appreciate the author’s attempt to familiarize your readers on this fascinating substance.

By: Jeffrey Florentino

Jeffrey Florentino — Fri, 05 Jul 2019 00:17:00 +0000

In reply to Robin W..

Thanks for your comment, we don’t answer personal health questions in the comments section for privacy reasons. To get answers to your health questions, please join SelfHacked VIP at https://selfhacked.lpages.co/selfhackedvip/. Feel free to get in touch with us with any questions about how our VIP members area works at support@selfhacked.com.

By: Robin W.

Robin W. — Sun, 30 Jun 2019 19:09:20 +0000

So, if one has +/+ NOS3, this probably should be avoided?

By: Ana Aleksic

Ana Aleksic — Fri, 09 Nov 2018 15:31:01 +0000

In reply to sohaib.

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By: sohaib

sohaib — Thu, 01 Nov 2018 01:58:36 +0000

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By: Stephanie Shan Russell [friends call me "Shan". ]

Stephanie Shan Russell [friends call me "Shan". ] — Sun, 28 Oct 2018 23:16:12 +0000

Thank you for sharing your information here. I have been reading for hours , and will be telling my doctor about this website. Hopefully I can afford your book next month.
best wishes, Shan

By: Fern Heloiza

Fern Heloiza — Sun, 16 Sep 2018 04:34:07 +0000

Hi there Walter Foster.
I’m very interested in hearing more details about your experience with the MG herbal mix from South Africa. Were you taking any meds for your MG at the time like the huperzine A or mestinon? Any interactions with the mix?
What were the ingredients?
Any healing reactions?

By: Rose Price

Rose Price — Sat, 11 Aug 2018 02:09:06 +0000

Hi, I have been taking a product for a while now that contains Huperzine A (300mcg). The product has replaced all my meds for depression, anxiety, and and I am very satisfied. This product has changed my life! But I am now pregnant. I cant find anything on risks or safety for the Huperzine A. All other ingredients I feel are safe so I would like to keep taking this product. I am afraid if I don’t I will end up back on a lot of pharmaceuticals w a lot of side effects.
Is there anyone who knows how this drug works that can tell me a more clear answer of safety or risk. I keep reading about it and it sounds good but since it crosses the placenta and blood brain barrier I just need to know more.
Thank you!! Please someone w any info let me know!

By: Concerned

Concerned — Sat, 11 Aug 2018 01:31:54 +0000

I have been taking a product that contains huperzine a (300mcg) and it has really improved my life. I have been able to completely stop taking pharmaceutical drugs for depression, anxiety and also adhd. Recently I have found out I am pregnant. I cant find anything that tells me if this is still safe to take or not. I’ve scoured the internet. If I quit taking it I am afraid ill end up back on all sorts of pharmaceuticals w side effects. Is this safe while pregnant? I know it crosses the placenta and the blood brain barrier but I can’t find anything I can see as being a bad thing for the baby. But I am also super scared to take it as I cant find anything on pregnancy and breastfeeding while taking this. Does anyone who truly understands how this substance works have any idea if it should be safe or if not why not?
Thank you!!!!
All other ingredients in this product I have researched and deemed safe but I just cannot make my mind up on this one.

By: Walter foster

Walter foster — Sat, 07 Jul 2018 04:09:25 +0000

I am a female patient with Myasthenia Gravis for 30 years and I have suffered tremendously because of this disorder. I had a thymectomy twenty five years ago and still have symptoms of MG. I came across Best Health Herbal Centre website after so many years researched through the internet. I was so desperate to find a way to treat this disorder naturally. Thank God for leading me to Best Health Herbal Centre. I started using Best Health Herbal Centre MG herbal formula this year. After 10 weeks of usage, my MG was totally reversed, symptoms like muscle weakness, difficulty swallowing, double vision, fatigue, impaired voice, or shortness of breath disappeared completely..Am now 67 years old living MG free.

By: Robert

Robert — Tue, 08 May 2018 02:07:50 +0000

I am starting to take this for simple memory loss. Early dementia?? Not sure. Wasn’t diagnosed. Just want to sharpen up the grey matter somewhat. Hoping this will enhance my life. I’ll report back in a month or so. The Hup-A that I bought is 300 mcg. I plan to start with 1 pill a day.

By: Shane

Shane — Thu, 08 Mar 2018 10:32:55 +0000

Hi,

I plan on taking this for another reason, but is there any evidence as this article suggests that this may help with the positive symptoms of schizophrenia??

By: Susan F Goryan

Susan F Goryan — Sun, 16 Jul 2017 15:33:58 +0000

Been on it for 5 years, shortly after diagnosis and a thymectomy. It works great, no side effects in all these years and I don’t have to take any other treatment. However, I supplement my diet with vitamin D3 and make sure to eat a good diet, get plenty of rest, make sure if I am having some weakness that I have a glass of milk or a protein bar, banana or even a bottle of Boost and slow down! I am usually doing way too much as I feel so well on just huperzine. It doesn’t work for every mg patient but has been such a wonderful alternative to what the doctor wanted to treat me with, which needed constant dosage increases!

By: Susan F Goryan

Susan F Goryan — Sun, 16 Jul 2017 15:27:49 +0000

Correction: I mean 100 mcg 2-4 times a day in milder months, NOT 2-4 mcg’s.

By: Susan F Goryan

Susan F Goryan — Sun, 16 Jul 2017 15:02:13 +0000

I have myasthenia gravis and am so, so lucky to have found huperzine-A within 6 months of my diagnosis and subsequent thymectomy. I take 100 mcg 4-6 times a day in summer months when heat can really slow me down and 2-4 mcg’s the rest of the year. It has gotten me off of the usual prescription drug and keeps me stable from the weakness and usual necessity of other treatments.
My neurologist would have me on constant RX drugs and plasma transfusions and I dropped him when he said NOT to take huperzine. Most doctors have no clue that their patients would rather use holistic and natural methods to live better lives, so doctors don’t know much about these alternate methods or seem afraid of them. Been on huperzine-only for more than 5 years and with a good diet and enough rest and listening to my body when I’m over doing something, I live a better life and am pretty active on huperzine….while I’m not in remission or cured, I am stable and without huperzine, I’d be on more & more drugs & treatments as the disease only has drastic treatments that only help for short periods…with huperzine, there are NO other treatments needed in my case!

By: Zhang Jian

Zhang Jian — Wed, 05 Jul 2017 01:22:49 +0000

Yes, Lu CZ was the most famous neurologist in CHINA. Sang GW is the academician of China National Engineering Resarch Institute. The research is reliable.

By: Milka

Milka — Wed, 05 Apr 2017 14:40:13 +0000

In reply to Natcha M. I have mg and I just started yesterday so far it seems that is working fine

By: Nattha Wannissorn

Nattha Wannissorn — Tue, 13 Dec 2016 14:42:44 +0000

In reply to Lee Ingram. Oh yes. Great catch. Thanks. Corrected.

By: Lee Ingram

Lee Ingram — Tue, 13 Dec 2016 08:18:22 +0000

just letting you know I see what I think must be a typo – I think 100mg should be 100mcg? here –

Dosage

For Alzheimer’s patients, a dosage of 0.4 mg twice daily was required to produce clinically significant results, as 0.2 mg twice daily did not (R).

Dosages of huperzine A in clinical trials for Alzheimer’s range from 0.2 mg to 0.8 mg (R).

In high school students who struggle with memory, 100 mg was sufficient to improve memory (R).

By: Ahmad Awadallah

Ahmad Awadallah — Mon, 12 Dec 2016 00:05:10 +0000

In reply to Natcha M. Thank you.

By: Natcha M

Natcha M — Sun, 11 Dec 2016 22:15:54 +0000

In reply to Ahmad Awadallah. Nope. It prevents or slow down break down of acetylcholine. You can't really supplement with acetylcholine but you can increase production or decrease breakdown.

By: Ahmad Awadallah

Ahmad Awadallah — Sun, 11 Dec 2016 18:32:24 +0000

Since HuperzineA breaks down Acetylcholine does this mean one should also supplement with Acetylcholine?

By: Natcha M

Natcha M — Sun, 11 Dec 2016 13:25:52 +0000

In reply to Lauri.

Hi Lauri, thanks for your comment.
I looked into the studies and found that there’s one single paper about Huperzine A for MG patients. This paper is in Chinese, and I could not look further into the details to assess the quality of the study so I decided not to include this point at first. Because, in principle, Huperzine A could really help with MG as an AchE inhibitor, I decided to add it to the post. If you find any other references about this, please let me know. A translation of the original Chinese article: Cheng YS, Lu CZ, Ying ZL, Ni WY, Zhang CL, Sang GW. 128 Cases of
myasthenia gravis treated with huperzine A. New Drugs Clin Remedies
1986;5:197– 9 will be very welcomed as well. ~Team SelfHacked

By: Lauri

Lauri — Sun, 11 Dec 2016 11:01:38 +0000

It is effective treatment for Myasthenia Gravis too.