Comments on: What is Coenzyme Q10 (CoQ10)? + Side Effects & Dosage

By: Samantha

Samantha — Sun, 27 Sep 2020 09:38:23 +0000

I greatly appreciate your life mission; for, you are serving humanity through better health.
Thank You.

By: Peter W Lindquist

Peter W Lindquist — Fri, 01 Nov 2019 23:58:58 +0000

Very informative, thank you, I am 65 and take no medicine, but I do take 200 mgs of CO Q 10 a day, and have been taking it for over 25 years.

By: David

David — Thu, 26 Sep 2019 13:57:10 +0000

Excellent review with lots of clinical references. Those of you still concerned with whether you need to take ubiquinone or ubiquinol – more and more absorption research is indicating that the form does not matter. I was reading about absorption research from Dr. William Judy, who found that ubiquinol is oxidized in the stomach before reaching the point of absorption in the small intestines. But the super interesting part about this research was that after absorption in the thoracic duct it had been converted back to ubiquinol again. The lesson here would suggest: The form is not important – ubiquinol is oxidized prior to absorption and becomes ubiquinone, however, the body cycles back and forth between the two forms anyways. Since the difference is a mere two electrons and ubiquinone is used in ATP production and its byproduct is ubiquinol. Ubiquinol’s primary function is as an antioxidant. The byproduct of ubiquinol donating two electrons to free radicals is ubiquinone. That should put the discussion of which form to take to rest – because it does not matter. The only thing that matters is that you buy a good, quality product with good absorption, no matter the form.

By: inggridmega

inggridmega — Wed, 28 Aug 2019 05:51:51 +0000

Coenzyme Q10 (CoQ10) is one of the endogenous antioxidants lipid soluble which can be used as an antiaging. CoQ10 is owned nature is not stable to light. One system that can be protected
CoQ10 from degradation is Solid Lipid Nanoparticle (SLN). SLN is a colloid carrier system with a core composed of lipids solid and surfactant. In topical use, the SLN system has an effect adhesive and occlusive which increases skin hydration. In addition, there are entrapment of drug molecules in the SLN system that is able to protect that molecule sensitive to the environment from degradation.

By: Hootan

Hootan — Tue, 06 Mar 2018 13:23:46 +0000

I’m still struggling between the whole discussion of Ubiquinol or Ubiquinone?? Which one is better?

By: Eva Marie Nohr

Eva Marie Nohr — Tue, 09 Jan 2018 10:30:21 +0000

Your articles are very well presented and deep.
No doubt its the best site I know for finding information about supplements.

QH combined with PQQ and NR/NADH is a great combo for mitochondrial support!

By: Katie

Katie — Wed, 27 Dec 2017 23:00:28 +0000

Thanks! I have considered bacopa, but then I was concerned about trying it since I found some info suggesting that it actually speeds up the pathway that converts tryptophan into serotonin. I am still open to trying it though, and I will definitely look into the others as well!

By: Brenden

Brenden — Wed, 27 Dec 2017 14:42:22 +0000

My wife has gene mutations preventing her from making dopamine. When dopamine is low, she gets mopey and sad. She also has MAOA and COMT gene mutations. When dopamine gets too high, she can’t metabolize it and get rid of it which makes her hulk out. She has issues with CoQ10 raising dopamine but has no issues at all with ubiquinol.

As an aside, if you have issues metabolizing neurotransmitters, methylcobolamin, adenosylcobalamin (different types of B12), D-Ribose and bacopa all help with too much neurotransmitters. You shouldn’t need all of them to help but at least you now have a list that you can try to see if it helps your situation.

By: Katie

Katie — Fri, 03 Nov 2017 22:31:42 +0000

Do CoQ10 or ubiquitol have MAO inhibition properties or raise serotonin or dopamine? I’m very sensitive to changes in brain chemistry and want to avoid these things.

Thanks