Comments on: Agomelatine (Valdoxan) Potential Uses & Side Effects

By: Lauren

Lauren — Fri, 18 Sep 2020 07:36:37 +0000

Hi, my dr just prescribed this and I’m just wondering about the effects on weight? I gained a lot on lexapro and he seems to think this will be better but I can’t find much info to back this. Thanks

By: Jeffrey Florentino

Jeffrey Florentino — Fri, 05 Jul 2019 00:14:16 +0000

In reply to FC.

Thanks for your comment, we don’t answer personal health questions in the comments section for privacy reasons. To get answers to your health questions, please join SelfHacked VIP at https://selfhacked.lpages.co/selfhackedvip/. Feel free to get in touch with us with any questions about how our VIP members area works at support@selfhacked.com.

By: FC

FC — Thu, 04 Jul 2019 10:44:31 +0000

So what are best solutions for protecting liver when taking Agomelatine?

By: alad

alad — Wed, 12 Jun 2019 14:16:58 +0000

I can concur with the immediate & unique effect of using this – even after considerable experience using melatonin supplements. The first night of use, I awoke early and quite refreshed. I felt far more clear, motivated and less anxious than typical in the mornings.

By: Nicky

Nicky — Mon, 27 May 2019 10:02:24 +0000

Taking 50 mg of valdoxan and have never had anxiety this severe before ( depression yes ,but not anxiety) so am going to stop after reading the earlier comment. Describing the anxiety as ‘crippling’ is spot on.

By: Caroline Lam

Caroline Lam — Wed, 21 Nov 2018 08:28:18 +0000

In reply to Holly.

Hi Holly,

Thank you for your comment. SelfHacked definitely doesn’t promote or want to promote any pharmaceuticals. We usually have natural alternatives listed for drugs, if available. But you’re right that there aren’t side effects listed for this particular drug, as we normally do for our drug posts. I’ll go ahead and add them in since I agree it’s important to mention!

Thanks again,
Caroline

By: Holly

Holly — Fri, 16 Nov 2018 05:51:17 +0000

Pretty disgusted that no side effects are listed here. Side effects are extremely common and can be serious. Irresponsible and lazy article writing. Or maybe getting kick-backs for only listing benefits. Don’t trust this site if it is only going to list benefits and ignore side effects!

By: Luna

Luna — Thu, 18 Oct 2018 12:52:34 +0000

In reply to Jacqui. After 2 weeks on 25 mg and 2 weeks on 50 mg there's been no weight gain or loss.

By: Jo

Jo — Tue, 16 Oct 2018 00:21:46 +0000

In reply to Jacqui. Not in my case. It gave me severe anxiety (never had before), especially in the morning. On 50mg the anxiety became crippling and then I started to develop paranoia. I discontinued Valdoxan and the anxiety went away.

By: Jacqui

Jacqui — Sun, 26 Aug 2018 14:21:34 +0000

Does this help anxiety?

By: Jacqui

Jacqui — Sun, 26 Aug 2018 14:19:55 +0000

Does this cause weight gain?

By: Shahzad

Shahzad — Tue, 31 Jul 2018 18:08:09 +0000

Any one help .i am on fluvoxamine 100mg then can i use combine use with agomelatine

By: timothy

timothy — Mon, 23 Jul 2018 07:26:20 +0000

update. My sleeping has began to settle and im falling asleep and waking up in a better sleeping pattern than before. My body is still adjusting from 25 to 50mg and im generally sensitive to medications. But I can see the improvements as everyday tasks and engaging with my interests and hobbies again gets better day by day.

By: Jordan

Jordan — Sun, 22 Jul 2018 10:13:08 +0000

I Just started this drug 3 days ago. I went to the GP and said I need help! After trying all sorts of medications and being mis diagnosed a few times I stopped everything! That was not a good move. Over the last 6 months I became such an angry person and couldnt sleep. I had nightmares every night and would hit the ground at a car backfiring. 4 days a go (day before seeing the GP I broke down! As a man that is hard to admit but I cried my eyes out and said how did I let myself get to this point. Anyway I said enough is enough. Saw the GP and said how can I be treated for Depression, Anxiety and PTSD? Without all the side effects. He told me to try Valdoxan and see how I go. The next day I felt like a new person, I still have a long way to go but I already feel a change in my mood and I feel happier. Cant wait to see how the next few weeks go. Hope to be a better husband and father.

By: Timothy

Timothy — Mon, 16 Jul 2018 17:50:31 +0000

This medication helped improve daily living and combat of anxiety & sadness to a small degree. Whilst the drug instantly makes you drowsy and sleepy it didn’t actually help improve my sleeping pattern very much, not sleeping until 5am was quite common.

By: Elizabeth

Elizabeth — Thu, 21 Jun 2018 13:53:19 +0000

Probably would have been better off just trying Melatonin to help sleep, then depression would lift a bit from getting a good sleep.

By: Elizabeth

Elizabeth — Thu, 21 Jun 2018 13:51:01 +0000

Update: day 9 and I hate Valdoxan for the nightmares, I have also put on 2kgs in that time, the anxiety has leveled out but the nightmares make it hard to go back to sleep once you wake up from nightmare, I still feel depressed but not as bad as before I went on Valdoxan. I went to sleep clinic today and specialist didn’t like me taking Valdoxan, said people should only be on it for a couple of months, not long term which then off course made me worry. I have had bit of swelling under base of rib cage which is what happend last time my liver played up. Will be seeing my doctor next week to request to be taken off it. It’s meant to help sleep, it doesnt if it gives you nightmares.

By: Petra

Petra — Thu, 21 Jun 2018 13:28:42 +0000

After a life time of dealing with debilitating winter SADS (Australia) and trying every antidepressants medication available with unbearable side effects and allergic reactions, my Psyciatrist put me onto Valdoxan and it has been my saving grace.
I start at 25mg and increase to 50mg after about a month for around 6 months a year, starting around April.
It stops my depression, anxiety and I can sleep and feel like a normal human during the cold months. I always felt helpless and doomed every winter and even though it is expensive, this medication is worth every cent.

By: Elizabeth

Elizabeth — Fri, 15 Jun 2018 17:28:29 +0000

I have been on 25mg of Valdoxan (agomeltatine) for 4 days now, for depression/sleep/pain and have noticed a significant difference in mood, not fluctuating hardly at all which it used to about 10 times a day, I have been on effexor, zoloft, prozac, mirtazone (i think that’s how it’s spelled) and a lot more but were years ago. Im interested in seeing the effects after a month, at the moment the one and only side effect i am getting is Nightmares each time i go to sleep, first night i was able to go back to sleep after nightmare (they seem to happen in first few hours of drifting off to sleep) then last night i woke wide awake after nightmare and couldn’t get back to sleep. I have Chronic Fatigue Syndrome, arthritis and have noticed a massive difference in pain as well which i’m extremely happy to say. I only want the nightmares to go away, will keep you updated as previous anti depressants have really done some damage from the side effects and bringing pain on worse and also making me feel depression worse. Oh i also do know that the melatonin in the drug can cause nightmares for some reason but i am hoping they will pass. I haven’t been angry or upset or burst into tears or felt frustrated with my life since day 3. yes it’s early days and yes the drug is expensive but compared to the amount of side effects other drugs have, the cost is worth it at this stage. I have tried SSRI’s, MAOI’s, Trycylic’s so let’s hope this is the one for me. p.s. i had suicidal thoughts last week (didn’t act on them though) and now……it’s the furtherest thing from my mind.

By: echuca1982@gmail.com

echuca1982@gmail.com — Tue, 12 Jun 2018 02:24:54 +0000

There is a Valdoxan Support Group on Facebook some 60 odd members run by I think a psychiatrist
Not the one with 17 members
Lots of posting

By: Deb

Deb — Sat, 09 Jun 2018 03:24:10 +0000

Hi all, My husband has just been prescribed this. Its darn expensive at nearly $70 for I think 20 tablets!

I am hoping this works on him as he is not sleeping, wish it was on the PBS.

Thanks for sharing your experiences. I will update to let you know how it affects him.

By: Derek

Derek — Mon, 04 Jun 2018 12:57:58 +0000

I was sceptical about Valdoxan, having tried other anti anxiety medications, non of which were satisfactory.
It’s not been 2 weeks yet, and this is a great medication. 1/- I’m now sleeping 6-8 hours solid 2/- have lost about 4 kilos already 3/- muscle strength and prominence is well evident 4/- no dizziness or headaches or anything detrimental 5/- anxieties have been vanished 6/- I have 3 times the energy and feel like I’m on a natural high 7/- I have completely stopped drinking alcohol and no longer overeat , just don’t feel the need to. All of this in 2 weeks, unbelievable improvement.

By: Pen

Pen — Wed, 30 May 2018 01:18:57 +0000

I have been taking this for 18 months now (in Australia). This was prescribed after having unmanageable side ffects with six SSRI prescriptions.
I have had no negative side effects. I started on 25mg for 6 months then went up to 50mg. My sleep has improved in that I can now get to sleep but I still cannot stay asleep so am averaging about 4 hours broken sleep a night.
There has been no adverse reactions when taking ant-anxiety medications and I (and my family) have noticed an increase in positive mood. Concentration has improved somewhat. All improvements have changed me from not beginning no able to leave my home or get out of bed some days, to getting regular everyday things done, like groceries, cooking cleaning etc. I have even now been able to start socializing in safe circles again.

It’s by no means a wonder drug, but it has changed my life for the better without hash side effects.

By: Diane

Diane — Mon, 28 May 2018 09:29:10 +0000

Very interested.After Years of trying to find an effective treatment. Huge weight gain, and many side effects, still not well, and so frustrated.